Golgi articles within Nature

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  • Article
    | Open Access

    A proteomics analysis demonstrates that, during nutrient stress, mammalian cells prioritize degradation by autophagy of membrane proteins and identifies receptors that mediate this process at the Golgi and also have a role in Golgi remodelling during neuronal differentiation.

    • Kelsey L. Hickey
    • , Sharan Swarup
    •  & J. Wade Harper

  • Letter |

    The COPI complex, which has a role in retrograde transport through the Golgi, is shown to also mediate anterograde tubular transport through the Golgi; in response to external stimuli, the small GTPase CDC42 acts as an essential modulator of bidirectional Golgi transport, and promotes the sorting of cargoes destined for anterograde transport into the tubules at the expense of those targeted for retrograde transport.

    • Seung-Yeol Park
    • , Jia-Shu Yang
    •  & Victor W. Hsu

  • Letter |

    Glucosylceramide (GlcCer), a common precursor of different glycosphingolipids, is shown to be channelled to two distinct pathways in the Golgi; non-vesicular transport from the cis- to trans-Golgi network results in the synthesis of the globo series of glycosphingolipids, whereas vesicular transport is the main source of GlcCer for ganglioside synthesis in the Golgi cisternae.

    • Giovanni D’Angelo
    • , Takefumi Uemura
    •  & Maria Antonietta De Matteis

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