Membrane curvature articles within Nature

Featured

• Article
  24 January 2024 | Open Access

  Motion of VAPB molecules reveals ER–mitochondria contact site subdomains

  High-speed molecular tracking is integrated with three-dimensional electron microscopy to map the diffusion distribution and ultrastructure of endoplasmic reticulum-mitochondria contact sites, revealing the ability of high-speed single-molecule imaging to map contact site interface structures and corresponding diffusion landscapes.

  • Christopher J. Obara
  • , Jonathon Nixon-Abell
  •  & Jennifer Lippincott-Schwartz

• Article | 17 December 2014

  Endophilin marks and controls a clathrin-independent endocytic pathway

  This study describes a fast, clathrin-independent endocytic pathway mediated by endophilin, dynamin and actin; the pathway is activated by ligand binding to a variety of cargo receptors, and endophilin-mediated endocytosis occurs primarily at the leading edges of cells where lamellipodin and the lipid PtdIns(3,4)P₂ ensure endophilin targeting.

  • Emmanuel Boucrot
  • , Antonio P. A. Ferreira
  •  & Harvey T. McMahon