Featured
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Letter |
Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour
Little is known about how individual cells within a group of cells exposed to the same external signals can produce a specific individual response to their local microenvironment; a quantitative analysis of cell crowding reveals that single cells can autonomously sense local crowding though their ability to spread and activate focal adhesion kinase (FAK), which ultimately results in changes in cellular lipid composition.
- Mathieu Frechin
- , Thomas Stoeger
- & Lucas Pelkmans
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Letter |
Interactome map uncovers phosphatidylserine transport by oxysterol-binding proteins
The lipid-binding profiles of all lipid-transfer proteins in Saccharomyces cerevisiae are determined and a new subfamily of oxysterol-binding proteins that function in phosphatidylserine homeostasis and transport is identified.
- Kenji Maeda
- , Kanchan Anand
- & Anne-Claude Gavin
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Letter |
Structure of the chemokine receptor CXCR1 in phospholipid bilayers
NMR spectroscopy is used to determine the three-dimensional structure of the full-length human chemokine receptor CXCR1 in phospholipid bilayers under physiological conditions.
- Sang Ho Park
- , Bibhuti B. Das
- & Stanley J. Opella
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News |
Cholesterol crawls
A study tracking cholesterol movement within membranes suggests that it travels more slowly than expected.
- Nic Fleming
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Research Highlights |
Vesicles form with pH shift
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Research Highlights |
Cell biology: Live-action lipids