Motor proteins articles within Nature

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  • Letter |

    Central spindle asymmetry, generated by the kinesin Klp10A and its antagonist Patronin, polarizes endosome motility and provides a mechanism for the asymmetric segregation of signalling endosomes observed in a variety of asymmetrically dividing cell types.

    • Emmanuel Derivery
    • , Carole Seum
    •  & Marcos Gonzalez-Gaitan

  • Letter |

    An optogenetic strategy allowing light-mediated recruitment of distinct cytoskeletal motor proteins to specific organelles is established; this technique enabled rapid and reversible activation or inhibition of the transport of organelles such as peroxisomes, recycling endosomes and mitochondria with high spatiotemporal accuracy, and the approach was also applied to primary neurons to demonstrate optical control of axonal growth by recycling endosome repositioning.

    • Petra van Bergeijk
    • , Max Adrian
    •  & Lukas C. Kapitein

  • Letter |

    Collective motion is a ubiquitous self-organization phenomenon that can be observed in systems ranging from flocks of animals to the cytoskeleton. Similarities between these systems suggest that there are universal underlying principles. This idea can be tested with 'active' or 'driven' fluids, but so far such systems have offered limited parameter control. Here, an active fluid is studied that contains only a few components — actin filaments and molecular motors — allowing the control of all relevant system parameters.

    • Volker Schaller
    • , Christoph Weber
    •  & Andreas R. Bausch

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