Featured
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Article |
Spin-enhanced nanodiamond biosensing for ultrasensitive diagnostics
Lateral-flow in vitro diagnostic assays based on fluorescent nanodiamonds, in which microwave-based spin manipulation is used to increase sensitivity, are demonstrated using the biotin–avidin model and by the single-copy detection of HIV-1 RNA.
- Benjamin S. Miller
- , Léonard Bezinge
- & Rachel A. McKendry
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Letter |
Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
The development of a nanoparticle RNA vaccine is reported that preferentially targets dendritic cells after systemic administration, and is shown to provide durable interferon-α-dependent antigen-specific immunity in mouse tumour models; initial results in advanced melanoma patients indicate potential efficacy in humans.
- Lena M. Kranz
- , Mustafa Diken
- & Ugur Sahin
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Outlook |
Nanotechnology: Carrying drugs
Traditional chemotherapies can be toxic but nano-sized carriers can keep them out of healthy tissue and take old drugs to new places.
- Katherine Bourzac
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Research Highlights |
Nanofibres foster blood vessels
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News |
Draft guidelines for nanomedicine unveiled
With hundreds of nanoproducts currently being tested in humans, recommendations aim to safeguard trial participants.
- Jessica Marshall
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Research Highlights |
Iron nanoparticles into blood
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News |
Diamonds deliver on cancer treatment
Carbon nanoparticles promise multifaceted benefits in transporting drugs.
- Marian Turner
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News |
Tiny traits cause big headaches
Nanotech medicines held up by lack of particle characterization.
- Daniel Cressey
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News Feature |
Nanotechnology: Small wonders
The US National Nanotechnology Initiative has spent billions of dollars on submicroscopic science in its first 10 years. Corie Lok finds out where the money went and what the initiative plans to do next.
- Corie Lok
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Research Highlights |
Cancer therapeutics: Nano tumour killer
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News |
Nanoparticle kit could diagnose disease early
Colour change shows the presence of minuscule amounts of key enzymes.
- Katharine Sanderson
Enantiomer-dependent immunological response to chiral nanoparticles