Neuromuscular junction articles within Nature

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• Letter | 01 August 2012

  Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses

  Lrp4 acts bidirectionally and coordinates synapse formation by binding agrin, activating MuSK and stimulating postsynaptic differentiation, and functioning in turn as a muscle-derived retrograde signal that is necessary and sufficient for presynaptic differentiation.

  • Norihiro Yumoto
  • , Natalie Kim
  •  & Steven J. Burden

• Letter | 18 March 2012

  Trans-synaptic Teneurin signalling in neuromuscular synapse organization and target choice

  Two Drosophila Teneurin proteins, Ten-m and Ten-a, are shown to be required for neuromuscular synapse organization and target selection.

  • Timothy J. Mosca
  • , Weizhe Hong
  •  & Liqun Luo