Neurotrophic factors articles within Nature

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  • Letter |

    Taste-receptor cells use distinct semaphorins to guide wiring of the peripheral taste system; targeted ectopic expression of SEMA3A or SEMA7A leads to bitter neurons responding to sweet tastes or sweet neurons responding to bitter tastes.

    • Hojoon Lee
    • , Lindsey J. Macpherson
    •  & Nicholas J. P. Ryba

  • Letter |

    Live fluorescent imaging of murine hippocampal slices shows that NMDAR-dependent glutamate signalling leads to postsynaptic BDNF release, with associated signalling of its receptor, TrkB, on the same dendritic spine, suggesting autocrine BDNF signalling.

    • Stephen C. Harward
    • , Nathan G. Hedrick
    •  & James O. McNamara

  • Letter |

    Igf1 is identified in mice as an experience-induced gene that functions cell-autonomously to increase inhibitory input onto a disinhibitory subtype of GABAergic neurons in the cortex, affecting the downstream excitation–inhibition balance within circuits that regulate visual acuity, and providing a novel example of experience modulating neural plasticity.

    • A. R. Mardinly
    • , I. Spiegel
    •  & M. E. Greenberg

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