Nucleotide-binding proteins articles within Nature

Featured

• Article | 07 September 2022

  Structure of dynein–dynactin on microtubules shows tandem adaptor binding

  The structure of the complete dynein–dynactin complex and its interaction with microtubules and cargo adaptors are visualized using cryo-electron microscopy.

  • Sami Chaaban
  •  & Andrew P. Carter

• Article
  20 July 2022 | Open Access

  Cryo-EM structure of an active bacterial TIR–STING filament complex

  Through structural analysis of the activation of bacterial STING, the molecular basis of STING filament formation and TIR effector domain activation in antiphage signalling is defined.

  • Benjamin R. Morehouse
  • , Matthew C. J. Yip
  •  & Philip J. Kranzusch

• Article | 11 March 2015

  Crystal structure of the eukaryotic origin recognition complex

  The crystal structure of the heterohexameric origin recognition complex (ORC), essential for coordinating DNA replication onset in eukaryotes, is resolved at 3.5 Å resolution.

  • Franziska Bleichert
  • , Michael R. Botchan
  •  & James M. Berger