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Open Access
Featured
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Article |
Multi-kingdom ecological drivers of microbiota assembly in preterm infants
Absolute microbial abundances delineate longitudinal dynamics of bacteria, fungi and archaea in the infant gut microbiome, uncovering drivers of microbiome development masked by relative abundances and revealing notable parallels to macroscopic ecosystem assemblies.
- Chitong Rao
- , Katharine Z. Coyte
- & Seth Rakoff-Nahoum
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Article
| Open Access
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017
A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.
- Roy Burstein
- , Nathaniel J. Henry
- & Simon I. Hay
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Letter |
Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth
Delivery via caesarean section, maternal antibiotic prophylaxis and colonization by opportunistic pathogens associated with the hospital environment affect the composition of the gut microbiota of children from birth until infancy.
- Yan Shao
- , Samuel C. Forster
- & Trevor D. Lawley
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Letter
| Open Access
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
An analysis of more than 10,000 metagenomes from the TEDDY study provides a detailed functional profile of the gut microbiome in relation to islet autoimmunity, and supports the protective effects of short-chain fatty acids in early-onset type 1 diabetes.
- Tommi Vatanen
- , Eric A. Franzosa
- & Ramnik J. Xavier
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Inside View |
Inside View: KAIMRC
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Books & Arts |
Genetics: Testing infant destinies
Henry Greely hails a study examining California's experience of mandatory newborn genetic screening.
- Henry T. Greely
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News |
Diuretic drug improves symptoms of autism
Small-scale trial provides hope for treatment of autistic behaviour in children.
- Mo Costandi
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Outlook |
Child development: The first steps
Because infants born into families with autism are more likely to develop the condition, studying them might lead to ways to diagnose people in the general population earlier.
- Katherine Bourzac
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News |
Brain connectivity predicts reading skills
Children could benefit from personalized lessons based on brain scans.
- Mo Costandi
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News |
Two-day test diagnoses genetic diseases in newborns
Platform could be a model for routine whole-genome sequencing in neonatal intensive care.
- Monya Baker
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Editorial |
Misplaced childhood
The US National Institutes of Health should rethink plans to limit a nationwide study of children. It must not miss a rare opportunity to probe the causes of childhood diseases.
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News |
Child-study turmoil leaves bitter taste
Frustration mounts as ambitious US project is scaled back.
- Meredith Wadman
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News |
Pre-term births on the rise
But simple measures could cut the mortality rate of premature babies in poorer countries.
- Eugenie Samuel Reich
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News |
Childhood drug studies show room for improvement
Report finds recent laws have enhanced US child medicine, but some drugs are still used without rigorous testing.
- Erika Check Hayden
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News |
Growing pains for children's study
Door-to-door recruitment abandoned for US project.
- Meredith Wadman
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News |
Vaccine campaign to target deadly childhood diarrhoea
Programme to guard against second-biggest killer of under-fives rolls out across Africa.
- Declan Butler
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News |
Genome study solves twins' mystery condition
Sequencing ends years of speculation over children's rare disorder.
- Erika Check Hayden
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News & Views |
How common is autism?
Autism spectrum disorders vary greatly in severity. By including children in regular education who received no special help, an epidemiological study has found these disorders to be up to three times more prevalent than thought.
- Catherine Lord
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Comment |
Children of the AIDS pandemic
Practical support and psychosocial interventions are desperately needed to help those dealing with the fallout of AIDS, says Lucie Cluver.
- Lucie Cluver
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News |
Stress can shorten telomeres in childhood
Children in orphanages have chromosome changes that could affect future health.
- Marian Turner
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News |
Home-birth study investigated
Criticism led journal to re-examine controversial paper that found higher death rate in babies born at home.
- Erika Check Hayden
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News |
Do gut bacteria worsen malnourishment?
Human microbiota could be behind why deficient diets leave only some children seriously ill.
- Nicola Jones
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Q&A |
Turning point: Collins Ouma
Molecular biologist Collins Ouma's efforts to combat paediatric malaria in Kenya are gaining momentum.
- Virginia Gewin
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News Explainer |
Is breast not best for babies?
New evidence contradicts World Health Organization breastfeeding advice.
- Natasha Gilbert
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News |
Kids swap DNA for fairground rides
Researchers' efforts to collect samples at a fair raise ethical questions.
- Ewen Callaway
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News |
Children who form no racial stereotypes found
Brain disorder eradicates ethnic but not gender bias.
- Janelle Weaver
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Research Highlights |
Genetics: Two strikes
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News |
Cot death victims make less serotonin
Mysterious infant deaths linked to chemical deficiency.
- Heidi Ledford
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News Feature |
Neuroscience: The most vulnerable brains
An increase in premature births means that more babies are at risk of neurological damage. Erika Check Hayden talks with researchers who are developing ways to help these children.
- Erika Check Hayden
Normative spatiotemporal fetal brain maturation with satisfactory development at 2 years