Parasite immune evasion articles within Nature

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• Article | 30 March 2022

  N⁶-methyladenosine in poly(A) tails stabilize VSG transcripts

  N⁶-methyladenosine is enriched in poly(A) tails of VSG transcripts in Trypanosoma brucei, and when lacking result in mRNA degradation.

  • Idálio J. Viegas
  • , Juan Pereira de Macedo
  •  & Luisa M. Figueiredo

• Letter | 29 November 2017

  Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

  Proteins expressed on the surfaces of erythrocytes infected with Plasmodium falciparum help the parasite to evade the host immune system by acting as ligands for immune inhibitory receptors and thereby downregulating the immune response.

  • Fumiji Saito
  • , Kouyuki Hirayasu
  •  & Hisashi Arase

• Letter | 03 July 2013

  PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum

  The malaria parasite Plasmodium falciparum escapes immune detection by expressing one of 60 antigenically distinct var genes at any one time during the course of infection: here it is shown that the P. falciparum protein PfSETvs has a key role in var gene silencing through the trimethylation of histone H3K36.

  • Lubin Jiang
  • , Jianbing Mu
  •  & Louis H. Miller