Peptide hormones articles within Nature

Featured

• Article | 08 December 2021

  A hormone complex of FABP4 and nucleoside kinases regulates islet function

  Hormonal FABP4 is discovered to be a pivotal regulator of an adipose–beta-cell endocrine axis that coordinates energy status and metabolic organ function, and targeting this axis improved metabolic outcomes.

  • Kacey J. Prentice
  • , Jani Saksi
  •  & Gökhan S. Hotamisligil

• News | 08 November 2010

  Growth factor makes a comeback in cystic fibrosis

  Work in pigs points to culprit and potential treatment for growth retardation.

  • Virginia Hughes

• Letter | 06 October 2010

  A redox switch in angiotensinogen modulates angiotensin release

  Angiotensins have a crucial role in blood pressure regulation and are generated by cleavage of a larger protein, angiotensinogen, by the enzyme renin. Structures of angiotensinogen alone and in complex with renin show that a large conformational change is required to expose the renin-cleavage site. The authors also show that this transition is regulated by oxidation and that women with pre-eclampsia have higher levels of the more active, oxidized, form.

  • Aiwu Zhou
  • , Robin W. Carrell
  •  & Randy J. Read

• Research Highlights | 24 February 2010

  Neuroscience: Baby blues