Protein databases articles within Nature

Featured

• Article
  06 March 2024 | Open Access

  Decoding chromatin states by proteomic profiling of nucleosome readers

  A multidimensional proteomics analysis of the interactions between around 2,000 nuclear proteins and over 80 modified dinucleosomes representing promoter, enhancer and heterochromatin states provides insights into how chromatin states are decoded by chromatin readers.

  • Saulius Lukauskas
  • , Andrey Tvardovskiy
  •  & Till Bartke

• Article
  19 July 2023 | Open Access

  Mega-scale experimental analysis of protein folding stability in biology and design

  Large-scale assays using cDNA display proteolysis are used to measure the folding stabilities of protein domains, providing a method to quantify the effects of mutations on protein folding, with applications in protein design.

  • Kotaro Tsuboyama
  • , Justas Dauparas
  •  & Gabriel J. Rocklin

• Article | 24 February 2021

  Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

  Spatial and temporal variations among individual human cell proteomes are comprehensively mapped across the cell cycle using proteomic imaging and transcriptomics.

  • Diana Mahdessian
  • , Anthony J. Cesnik
  •  & Emma Lundberg