Proteome informatics articles within Nature

Featured

  • Article
    | Open Access

    A multidimensional proteomics analysis of the interactions between around 2,000 nuclear proteins and over 80 modified dinucleosomes representing promoter, enhancer and heterochromatin states provides insights into how chromatin states are decoded by chromatin readers.

    • Saulius Lukauskas
    • , Andrey Tvardovskiy
    •  & Till Bartke
  • Article
    | Open Access

    Blood plasma protein data was combined with machine learning models for a simple method to determine differences in organ-specific aging; the study provides a basis for the prediction of diseases and aging effects using plasma proteomics.

    • Hamilton Se-Hwee Oh
    • , Jarod Rutledge
    •  & Tony Wyss-Coray
  • Article |

    Protein immunofluorescence imaging and affinity purification–mass spectrometry are combined to create a unified map of human cell architecture across scales, which the authors call the multi-scale integrated cell (MuSIC).

    • Yue Qin
    • , Edward L. Huttlin
    •  & Trey Ideker