Small GTPases articles within Nature

Featured

• Article | 18 May 2022

  Intracellular lipid surveillance by small G protein geranylgeranylation

  In Caenorhabditis elegans, geranylgeranyl conjugation to RAB-11.1 acts as a lipid sensor to regulate nutrient uptake and lipid metabolism in response to metabolic demand.

  • Abigail Watterson
  • , Lexus Tatge
  •  & Peter M. Douglas

• Letter | 24 August 2016

  An endosomal tether undergoes an entropic collapse to bring vesicles together

  A new endosomal tethering mechanism involving a mechanochemical cycle of the dimeric coiled-coil protein EEA1 regulated by Rab5:GTP binding and GTP hydrolysis.

  • David H. Murray
  • , Marcus Jahnel
  •  & Marino Zerial