Volume 41 Issue 10, October 2020
Cartoon depicting various representative molecules in the Ca2+ channel complex that regulate Ca2+ transfer at mitochondriaassociated ER membranes (MAMs). ER endoplasmic reticulum, IMM inner mitochondrial membrane, OMM outer mitochondrial membrane, MFN1/2 mitofusin 1/2, MCU mitochondrial calcium uniporter, NCLX Na+/Ca2+/Li+ permeable exchanger, VDAC1 voltage-dependent anion channel, IP3R inositol 1,4,5-triphosphate receptor, GRP75 chaperone 75 kDa glucose-regulated protein, FUNDC1 FUN14 domain containing 1, Sig-1R the sigma-1 receptor, PTPIP51 protein tyrosine phosphatase-interacting protein 51, and VAPB vesicle-associated membrane proteinassociated protein B.
