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Volume 45 Issue 5, May 2024

Cover Credit: Following MIR, MCMECs release GMCSF to recruit monocyte infiltration, which in turn releases CCL2 to induce CCR2+ immune cell infiltration. GMCSF transits CCR2+ macrophages to M1 phenotype, mediating and amplifying inflammation that exacerbates MIR injury, while CCL2 transits CCR2+ macrophages to M2 phenotype, mediating fibrotic remodeling after MIR.

Volume 45 Issue 5

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