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Pullusurfactins A‒C, new biosurfactants produced by Aureobasidium pullulans A11231-1-58 from Chrysanthemum boreale Makino

The Journal of Antibiotics volume 76, pages 741–745 (2023)Cite this article

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Abstract

Biosurfactants have found widespread use across multiple industrial fields, including medicine, food, cosmetics, detergents, pulp, and paper, as well as the degradation of oil and fat. The culture broth of Aureobasidium pullulans A11231-1-58 isolated from flowers of Chrysanthemum boreale Makino exhibited potent surfactant activity. Surfactant activity-guided fractionation led to the isolation of three new biosurfactants, pullusurfactins A‒C (1‒3). Their chemical structures were established through the use of spectroscopic techniques, predominantly 1D and 2D NMR, in conjunction with mass measurements. We evaluated the surface tension activities of isolated compounds. At 1.0 mg l−1, these compounds showed high degrees of surfactant activity (31.15 dyne/cm, 33.75 dyne/cm, and 33.83 dyne/cm, respectively).

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Acknowledgements

This work was partially supported by Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry (IPET) through Crop Viruses and Pests Response Industry Technology Development Program, funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA) (grant number 321103-3). Authors thank Ms. Ji-Young Oh, Center for University-wide Research Facilities (CURF) at Jeonbuk National University, for performing the NMR measurements.

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  1. These authors contributed equally: Jong-Shik Kim, Dae-Won Ki

Authors and Affiliations

  1. Marine Industry Research Institute for East sea rim, Uljin, Korea

    Jong-Shik Kim

  2. Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, Korea

    Dae-Won Ki, In-Kyoung Lee & Bong-Sik Yun

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  1. Jong-Shik Kim
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  2. Dae-Won Ki
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Kim, JS., Ki, DW., Lee, IK. et al. Pullusurfactins A‒C, new biosurfactants produced by Aureobasidium pullulans A11231-1-58 from Chrysanthemum boreale Makino. J Antibiot 76, 741–745 (2023). https://doi.org/10.1038/s41429-023-00660-9

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  • DOI: https://doi.org/10.1038/s41429-023-00660-9

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