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Fundus autofluorescence imaging in chronic optic pit maculopathy: prognostic implications

Eye volume 38, pages 1014–1016 (2024)Cite this article

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Subretinal fluid (SRF) is the most consistent marker for poor visual prognosis in optic pit maculopathy (OPM), and early indication for surgery across the largest and most recent studies on surgery and natural history of OPM [1, 2]. Optical coherence tomography (OCT) is the key imaging modality for OPM. Fundus autofluorescence imaging (FAF) has only been used as an adjunct to OCT so far, with descriptive rather than prognostic additional information [3, 4]. We report the prognostic value of FAF in chronic OPM.

FAF showed confluent hypoautofluorescence in 5/8 (62%) patients, indicating diffuse RPE atrophy (Fig. 1b, h). Four of these were operated: three gained 2–4 Snellen lines; one failed to improve. The one not operated had spontaneously settled maculopathy (BCVA 2/60). The confluent hypoautofluorescence in the four operated cases remained unchanged despite the functional and anatomical improvement. Mean final BCVA of these 5 cases with confluent hypoautofluorescence was 6/24 (median: 6/18). Three cases showed no evidence of RPE atrophy on FAF: all improved by 3–4 Snellen lines; two improved to 6/6–6/9 (mean final BCVA: 6/12; median: 6/9) (Fig. 1e–g).

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Fig. 1: Fundus autofluorescence and optical coherence tomography features in chronic optic pit maculopathy.

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The data generated or analyzed during this study are included in this published article; Supplementary Information is available with the corresponding author.

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Authors and Affiliations

  1. Retina-Vitreous Service, Ratan Jyoti Netralaya, Gwalior, India

    Dhananjay Shukla

  2. Vitreous Retina Macula Specialists of Toronto, Toronto, ON, Canada

    Anuradha Dhawan

  3. Department of Ophthalmology, NMC Specialty Hospital, Abu Dhabi, UAE

    Jay Kalliath

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  1. Dhananjay Shukla
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  2. Anuradha Dhawan
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  3. Jay Kalliath
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Contributions

DS, AD, and JK: conceptualization; DS and JK: methodology and data collection; DS and AD: validation; AD: formal analysis; DS: resources; AD and JK: data curation; DS, AD, and JK: writing; all authors approved the final draft.

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Correspondence to Dhananjay Shukla.

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Shukla, D., Dhawan, A. & Kalliath, J. Fundus autofluorescence imaging in chronic optic pit maculopathy: prognostic implications. Eye 38, 1014–1016 (2024). https://doi.org/10.1038/s41433-023-02792-6

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  • DOI: https://doi.org/10.1038/s41433-023-02792-6

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