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Dementia

Multisite chronic pain: a risk factor for dementia

Nature Reviews Neurology volume 19, pages 331–332 (2023)Cite this article

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A study of more than 350,000 individuals has shown that multisite chronic pain is strongly correlated with elevated risk of dementia, decreased cognitive function and reduced hippocampal volume. Further study of these relationships and their potential underlying mechanisms is required and could inform the development of interventions to prevent or slow dementia.

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Authors and Affiliations

  1. Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Hongxin Dong

  2. Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Hongxin Dong

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  1. Hongxin Dong
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Correspondence to Hongxin Dong.

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The authors declare no competing interests.

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Dong, H. Multisite chronic pain: a risk factor for dementia. Nat Rev Neurol 19, 331–332 (2023). https://doi.org/10.1038/s41582-023-00807-0

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