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The global patent landscape of mRNA for diagnosis and therapy

Nature Biotechnology volume 41, pages 1193–1199 (2023)Cite this article

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The COVID-19 pandemic brought mRNA vaccines to market in a short period, pointing the entire drug development field in the direction of mRNA treatment.

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Fig. 1: Flow diagram of patent documents included in patent landscape analysis.
Fig. 2: Trend in mRNA patent applications during the study period.
Fig. 3: Collaboration networks of inventors and assignees.
Fig. 4: Characteristics of mRNA patents.
Fig. 5: mRNA patent citation frequency.

Data availability

All data in this study are available from the corresponding author upon request. Source data are provided with this paper.

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Acknowledgements

This work was supported by the National Natural Science Foundation of China (grants no. 81972392, 82102902, 82272769).

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Author notes

  1. These authors contributed equally: Mengru Lyu, Jiyuan Chen, Yeheng Peng.

Authors and Affiliations

  1. Department of Clinical Pharmacy and Pharmaceutical Management, School of Pharmacy, Fudan University, Shanghai, China

    Mengru Lyu, Yeheng Peng, Luyao Gong & Yuan Gao

  2. Department of Clinical Pharmacy, School of Life Sciences and Biopharmaceutical Sciences, Shenyang Pharmaceutical University, Shenyang, China

    Mengru Lyu, Fang Han, Jingfei Guo & Lijuan Tian

  3. Department of Pharmacy, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University, Shanghai, China

    Jiyuan Chen

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  1. Mengru Lyu
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Corresponding author

Correspondence to Yuan Gao.

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Nature Biotechnology thanks Mario Gaviria for his contribution to the peer review of this work.

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Lyu, M., Chen, J., Peng, Y. et al. The global patent landscape of mRNA for diagnosis and therapy. Nat Biotechnol 41, 1193–1199 (2023). https://doi.org/10.1038/s41587-023-01925-2

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