Defining minimal standards for data collection is key to creating interoperative, searchable genomic and clinical databases. We highlight here the 1+Million Genomes Minimal Dataset for Cancer, encompassing 140 items in 8 domains to foster the collection of cancer data, inform transnational cooperation and advance precision cancer medicine.
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Data availability
The 1+MG-MDC is maintained in Zenodo (https://doi.org/10.5281/zenodo.10784601)16.
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Acknowledgements
We wish to thank the 1+MG WG9 community for helpful comments and discussion, as well as the members of the Center for Omics Sciences, at the San Raffaele Scientific Institute in Milan. The B1MG project has received funding from the EU Horizon 2020 research and innovation program under grant agreement no. 951724. The GDI project receives funding from the EU Digital Europe program under grant agreement no. 01081813. This work was also supported by the CCM 2021 ‘Italian Genomics Strategy: establishment of a steering committee to support the European initiative 1+MG and Beyond 1+MG (B1MG) and the Inter-institutional Coordination for Genomics in Public Health’ project.
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R.R. has received honoraria from AbbVie, AstraZeneca, Janssen, Illumina, and Roche. G.T. has received honoraria from Janssen, Adaptive Biotechnologies and Diasorin. The other authors do not report competing interests.
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Nature Genetics thanks Andrew Biankin and George Vassiliou for their contribution to the peer review of this work.
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Riba, M., Sala, C., Culhane, A.C. et al. The 1+Million Genomes Minimal Dataset for Cancer. Nat Genet 56, 733–736 (2024). https://doi.org/10.1038/s41588-024-01721-x
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DOI: https://doi.org/10.1038/s41588-024-01721-x
