Nature Outline 

Cancer vaccines

The use of vaccines not to prevent illness but as treatments, rallying the immune system to attack existing tumours, has the potential to revolutionize cancer therapy.

abstract illustration meant to show cancer cells being broken up by lightening bolt

Nature is pleased to acknowledge financial support from Moderna in producing this Outline. The sponsor retains sole responsibility for the following message.

Over the past 30 years, researchers have learned how to engineer stable forms of mRNA and deliver these molecules to the body through vaccines. The COVID-19 pandemic with the speedy design, manufacturing, and testing of mRNA COVID-19 vaccines has put a spotlight on the potential for mRNA as a therapeutic across multiple disease processes not only in the field of infectious diseases but also immuno-oncology and rare diseases. Moderna is reimagining how medicines are made for a wide range of diseases and conditions, such as cancer.
Moderna strives to deliver the greatest possible impact to people through mRNA medicines. Moderna’s mission is to research and develop new cancer medicines using an mRNA platform with the goal of training the immune system to recognize cancer cells and launch an immune response. Moderna continues to expand the portfolio of investigational candidates that are being studied in oncology.

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