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Insulin-like growth factor signalling

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Insulin-like growth factor signalling encompasses a highly conserved system of ligands, receptors, and binding proteins that impact somatic growth by regulating cellular growth, differentiation, and survival. This system also plays a crucial role in carbohydrate metabolism, stem cell maintenance, and aging. Growing evidence also points to the involvement of these signaling pathways in cancer progression.  

This Collection welcomes original research on all aspects of insulin-like growth factor signalling, from structural chemistry through cell biology and clinical medicine.

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Insulin-like growth factor 1 (IGF-1), molecular model. IGFs are polypeptides that are similar in their molecular structure to insulin

Editors

  • Ernestina Marianna De Francesco, PhD  &

    Ernestina Marianna De Francesco, PhD

    Department of Medicine and Surgery, “Kore” University of Enna, Enna, Italy

  • Antonio Villalobo, MD, PhD

    Antonio Villalobo, MD, PhD

    Cancer and Human Molecular Genetics Area, University Hospital La Paz Research Institute (IdiPAZ), Madrid, Spain

Articles will be displayed here once they are published.