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New findings indicate a role for SMN protein in assembly of the synaptic SNARE complex at neuromuscular junctions, providing insight into mechanisms of pathology in spinal muscular atrophy.
Thalamic activity onto a sparse population of premotor neurons in the zebra finch song nucleus initiates syllable onset, enabling the orchestration of song production.
Infant attachment to the mother in rodents and monkeys is shown to rely on regulation of hypothalamic oxytocin release by a serotonergic projection from the raphe nucleus.
Seung-Hee Lee describes findings published in 2000 that gave us insight into the principles by which different types of GABAergic synapses are organized in cortical networks.
A 1997 paper, described here by Hiromasa Takemura, showed that variations in the size of the visual cortex in humans are correlated with those of other parts of the visual system.
The CNS critically relies on an extensive and complex vasculature to function properly. In this Review, Wälchli and colleagues examine the general and CNS-specific mechanisms that underlie angiogenesis in brain development, brain vascular malformations and brain tumours.
Clarification of mechanisms underlying inflammation and neural repair after ischaemic stroke could lead to improved prognosis. In this Review, Shichita et al. discuss the biphasic nature of the post-stroke inflammatory response and the key molecules and cells involved.
In this Perspective, Floegel et al. examine two perspectives — musculoskeletal plant control and perceptual control — on modelling human motor control. They discuss the implications of adopting one or the other perspective when conducting such modelling and the consequences for our understanding of actions.
