Connective tissue diseases articles within Nature

Featured

• Article | 30 January 2019

  PU.1 controls fibroblast polarization and tissue fibrosis

  The transcription factor PU.1 is an essential regulator of the pro-fibrotic gene expression program in fibroblasts; PU.1 expression is upregulated in various fibrotic diseases, whereas inactivation of PU.1 induces regression of fibrosis in a number of organs.

  • Thomas Wohlfahrt
  • , Simon Rauber
  •  & Andreas Ramming

• News | 26 August 2010

  The skin disease that cures itself

  Diseased cells have harnessed a cancer-causing mechanism to banish a mutant gene.

  • Ewen Callaway