Olfactory receptors articles within Nature

Featured

  • Article
    | Open Access

    Messenger RNAs transcribed from olfactory-receptor genes may have non-coding functions that include recruitment of transcriptional enhancers and inhibition of potentially thousands of competing alleles to ensure stable transcription of a single allele.

    • Ariel D. Pourmorady
    • , Elizaveta V. Bashkirova
    •  & Stavros Lomvardas

  • Article |

    Through the use of cryo-electron microscopy and molecular dynamics stimulations, mechanistic insight into the binding of an odorant to the human odorant receptor OR51E2 is provided.

    • Christian B. Billesbølle
    • , Claire A. de March
    •  & Aashish Manglik

  • Article |

    Odour motion contains valuable directional information that is absent from the airflow alone, and Drosophila use this directional information to shape their navigational decisions.

    • Nirag Kadakia
    • , Mahmut Demir
    •  & Thierry Emonet

  • Article |

    A neurogenetic model, Drosophila sechellia—a relative of Drosophila melanogaster that has developed an extreme specialization for a single host plant—sheds light on the evolution of interspecific differences in behaviour.

    • Thomas O. Auer
    • , Mohammed A. Khallaf
    •  & Richard Benton

  • Article |

    A cryo-electron microscopy structure of the insect Orco subunit, which forms ion channels with diverse olfactory receptors, reveals a tetrameric cation channel and sheds light on insect olfaction.

    • Joel A. Butterwick
    • , Josefina del Mármol
    •  & Vanessa Ruta

  • Letter |

    Drosophila sechellia, a species closely related to the model species Drosophila melanogaster, bypasses a premature stop codon in neuronal cells to express a functional olfactory receptor protein from an assumed pseudogene template.

    • Lucia L. Prieto-Godino
    • , Raphael Rytz
    •  & Richard Benton

  • Article |

    The mosquito Aedes aegypti includes two subspecies, one of which shows a preference for biting humans, whereas the other prefers to bite non-human animals; genetic analysis reveals that changes in the mosquito odorant receptor Or4 contribute to the behavioural difference—in human-preferring mosquitoes, Or4 is more highly expressed and more sensitive to sulcatone, a compound present at high levels in human odour.

    • Carolyn S. McBride
    • , Felix Baier
    •  & Leslie B. Vosshall

  • Article |

    The olfactory receptors and neurons that recognize the insect repellent DEET have been identified in Drosophila melanogaster, enabling identification of new insect repellents in a chemical screen and offering another research avenue against diseases transmitted by insects.

    • Pinky Kain
    • , Sean Michael Boyle
    •  & Anandasankar Ray

  • News & Views |

    It's a touching story of cohabitation and meaningful communication. Two neighbouring fruitfly neurons talk to each other not by means of synaptic junctions but by interactions through the surrounding electrical field. See Article p.66

    • Kazumichi Shimizu
    •  & Mark Stopfer

  • Article |

    Olfactory receptor neurons of fruitflies are shown to communicate with one another through ephaptic interactions with significant impact on olfactory behaviour; the results indicate that ephaptic effects may be more widespread than previously appreciated.

    • Chih-Ying Su
    • , Karen Menuz
    •  & John R. Carlson

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