Patch clamp articles within Nature

Featured

• Article
  22 September 2021 | Open Access

  Structural basis of gating modulation of Kv4 channel complexes

  Cryo-electron microscopy structures of the voltage-gated potassium channel Kv4.2 alone and in complex with auxiliary subunits (DPP6S and/or KChIP1) reveal the distinct mechanisms of these two different subunits in modulating channel activity.

  • Yoshiaki Kise
  • , Go Kasuya
  •  & Osamu Nureki

• Letter | 11 October 2017

  Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3

  A cryo-electron microscopy structure shows that the mucolipin domain of the lysosomal calcium channel TRPML3 binds phosphatidylinositol-3,5-bisphosphate and gates the channel.

  • Marscha Hirschi
  • , Mark A. Herzik Jr
  •  & Seok-Yong Lee