Volume 28 Issue 7, July 2023

Human monocyte-derived microglia (MDMi) (labelled for tubulin in green) infected with SARS-CoV-2 (upper panel) showing the formation of a characteristic inflammasome ASC speck (in red). Lower panel shows LPS-primed MDMi treated with the microbial toxin nigericin, as a positive control for NLRP3 inflammasome activation. Cell nuclei are stained with DAPI (blue). For more information see the article by Albornoz et al. on pages 2878-2893.